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当前位置: 首页 > 产品中心 > peptide > 顶生系统/人类TOP2A/TOP2蛋白质,无标签/500ug/TOA
商品详细顶生系统/人类TOP2A/TOP2蛋白质,无标签/500ug/TOA
顶生系统/人类TOP2A/TOP2蛋白质,无标签/500ug/TOA
顶生系统/人类TOP2A/TOP2蛋白质,无标签/500ug/TOA
商品编号: TOA
品牌: ACROBiosystems
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 多肽合成
公司分类: peptide
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Synonym
    TOP2A,TOP2,DNA topoisomerase 2-alpha,DNA topoisomerase II,alpha isozyme
  • Source
    Human TOP2A, Tag Free (TOA-H5117) is expressed from E.coli cells. It contains AA Ser 1354 - Ser 1473 (Accession # P11388-1).
    Predicted N-terminus: Met
    Request for sequence
  • Molecular Characterization
    Online(Ser 1354 - Ser 1473) P11388-1

    This protein carries no "tag".

    The protein has a calculated MW of 12.8 kDa. The protein migrates as 20 kDa under reducing (R) condition (SDS-PAGE).

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Delivered as bulk protein in a 0.2 μm filtered solution of 50 mM Tris, 0.5 M KCl, pH8.0 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • Shipping
    This product is supplied as sterile liquid solution and shipped frozen with dry ice, please inquire the shipping cost.
SDS-PAGE
Human TOP2A, Tag Free (Cat. No. TOA-H5117) SDS-PAGE gel

Human TOP2A, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

  • Background
    DNA topoisomerase 2-alpha (TOP2A) is also known as DNA topoisomerase II, alpha isozyme and TOP2. It is a topoisomerase which control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. Also it is the targets of anti-cancer drugs that cause treatment-related leukemias with balanced translocations.
  • References
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

品牌介绍
ACROBiosystems 是一个具有全球范围影响力的生物技术领导品牌,其运营包括了位于北美、 欧洲和亚洲的数家公司, 主要为生命科学研究、生物制药与疫病诊断等行业提供产品、技术服务和临床应用等解决方案,同时致力于在蛋白组学、药物发现和细胞治疗等领域推广面向工业化和临床转化的技术和产品。ACROBiosystems 的业务遍及全球50多个国家和地区,并通过在北美、亚洲、欧洲等世界范围的不同时区设立分支机构以服务于当地客户与经销商。