- SynonymVSIG2,CT-like protein,CTH,CTXL
- SourceHuman VSIG2, His Tag (VS2-H5225) is expressed from human 293 cells (HEK293). It contains AA Val 24 - Ala 243 (Accession # AAH07313).Predicted N-terminus: Val 24Request for sequence
- Molecular Characterization
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 24.4 kDa. The protein migrates as 25-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- EndotoxinLess than 1.0 EU per μg by the LAL method.
- Purity
>95% as determined by SDS-PAGE.
- Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
- Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
- Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
Human VSIG2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
- BackgroundV-set and immunoglobulin domain-containing protein 2 (VSIG2) is also known as Cortical thymocyte-like protein, CTH, CTXL, is a single-pass type I membrane protein which contains Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. V-set domains are Ig-like domains resembling the antibody variable domain. VSIG2 is highly expressed in stomach, colon, prostate, trachea and thyroid glands and weakly in bladder and lung. V-set domains are found in diverse protein families, including immunoglobulin light and heavy chains.
- References
- (1)Chretien I., et al., 1998, Eur. J. Immunol. 28:4094-4104.
- (2)Zhang Z., et al., 2004, Protein Sci. 13:2819-2824.
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