- SynonymASCT2,M7V1,RDR,RDRC,ATB(0),AAAT,ASCT2M7VS1,M7V1ATBO,R16,RD114,RDRCFLJ31068
- SourceHuman SLC1A5, His Tag, TrxA Tag (SL5-H5149) is expressed from E.coli cells. It contains AA Gln 154 - Gln 224 (Accession # Q15758-1).Predicted N-terminus: Met
- Molecular Characterization
This protein carries a polyhistidine tag at the N-terminus, followed by a TrxA tag.
The protein has a calculated MW of 22.5 kDa.
- EndotoxinLess than 1.0 EU per μg by the LAL method.
- Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
- Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
- Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
- BackgroundSodium-dependent amino acids transporter(SLC1A5) that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904).
- References
(1)Kekuda R., etal. 1996, J Biol Chem., 271(31), 18657-61.
(2)Blond JL., etal. 2000, J Virol., 74(7), 3321-9.
(3)Sugimoto J., etal. 2017,Sci Rep., 3,1462.
Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.
