ACROBiosystems/Cynomolgus PADI2 Protein, His Tag/50ug/PA2
商品编号：
PA2
品牌：
ACROBiosystems
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
- SynonymPADI2,PAD-H19,KIAA0994,PAD2,PDI2
- SourceCynomolgus PADI2, His Tag (PA2-C5146) is expressed from E.coli cells. It contains AA Met 1 - Pro 665 (Accession # A0A2K5TST4-1).
- Molecular Characterization
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 77.6 kDa.
- Endotoxin
- Formulation
Delivered as bulk protein in a 0.2 μm filtered solution of PBS, pH7.4 with glycerol as protectant.
Contact us for customized product form or formulation.
- Storage
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- The product MUST be stored at -70°C or lower upon receipt;
- -70°C for 3 months under sterile conditions.
- ShippingThis product is supplied as sterile liquid solution and shipped frozen with dry ice, please inquire the shipping cost.
- BackgroundProtein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer.This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.
- References
- (1)Slade DJ, et al. ACS Chem Biol. 2015. 10(4):1043-53.
- (2)Ishigami A, et al. Arch Biochem Biophys. 2002. 407(1):25-31.
- (3)Wang L, et al. Cancer Res. 2017. 77(21):5755-5768.
Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.
品牌介绍
ACROBiosystems 是一个具有全球范围影响力的生物技术领导品牌，其运营包括了位于北美、 欧洲和亚洲的数家公司， 主要为生命科学研究、生物制药与疫病诊断等行业提供产品、技术服务和临床应用等解决方案，同时致力于在蛋白组学、药物发现和细胞治疗等领域推广面向工业化和临床转化的技术和产品。ACROBiosystems 的业务遍及全球50多个国家和地区，并通过在北美、亚洲、欧洲等世界范围的不同时区设立分支机构以服务于当地客户与经销商。
