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当前位置: 首页 > 产品中心 > cytokine > ACROBiosystems/人MICA蛋白,Fc标签/100ug/MIA
商品详细ACROBiosystems/人MICA蛋白,Fc标签/100ug/MIA
ACROBiosystems/人MICA蛋白,Fc标签/100ug/MIA
ACROBiosystems/人MICA蛋白,Fc标签/100ug/MIA
商品编号: MIA
品牌: ACROBiosystems
市场价: ¥30000.00
美元价: 15000.00
产地: 美国(厂家直采)
公司:
产品分类: 细胞因子
公司分类: cytokine
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
  • Synonym
    MIC-A
  • Source
    Human MICA, Fc Tag (MIA-H5253) is expressed from human 293 cells (HEK293). It contains AA Glu 24- Trp 307 (Accession # AAH16929.1).
    Predicted N-terminus: Glu 24
  • Molecular Characterization
    Online-Res(Glu 24- Trp 307) AAH16929.1

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 59.0 kDa.

  • Endotoxin
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.
  • References
    • (1)Groh V., et al., 1998, Science 279:1737-1740.
    • (2)Bauer S., et al., 1999, Science 285:727-729.
    • (3)Steinle A., et al., 2001, Immunogenetics 53:279-287.
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

品牌介绍
ACROBiosystems 是一个具有全球范围影响力的生物技术领导品牌,其运营包括了位于北美、 欧洲和亚洲的数家公司, 主要为生命科学研究、生物制药与疫病诊断等行业提供产品、技术服务和临床应用等解决方案,同时致力于在蛋白组学、药物发现和细胞治疗等领域推广面向工业化和临床转化的技术和产品。ACROBiosystems 的业务遍及全球50多个国家和地区,并通过在北美、亚洲、欧洲等世界范围的不同时区设立分支机构以服务于当地客户与经销商。